Early diagnosis of keratoconus using corneal biomechanics and OCT derived technologies.

Journal: Eye and vision (London, England)
Published Date: May 12, 2025

Abstract

BACKGROUND: Early detection of keratoconus is essential for maximizing the potential of cross-linking treatments designed to halt keratoconus progression, minimizing the risks of iatrogenic ectasia as well as reducing the need for corneal transplantation. This review focuses on the progress that has been made in the early detection of keratoconus using biomechanical and topographical properties derived from three different technologies, namely the ocular response analyser (ORA), corneal visualization Scheimpflug tonometer (Corvis ST) and optical coherence tomography (OCT).

Authors

  • Xiaorui Wang
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK.
  • Sayo Maeno
    Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Yixin Wang
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK.
  • Shizuka Koh
    Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Shihao Chen
    Wenzhou Medical University, Wenzhou, China.
  • Andrew J Quantock
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK.
  • Siân R Morgan
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK.
  • Sally Hayes
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK.
  • Colm McAlinden
    Wenzhou Medical University, Wenzhou, China. colm.mcalinden@gmail.com.

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