Efficacy and Safety of rVIII-SingleChain in Surgical Prophylaxis.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia
Published Date: May 10, 2025

Abstract

INTRODUCTION: RVIII-SingleChain is a B-domain-truncated factor VIII construct with a covalent bond between the factor VIII heavy and light chains.

Authors

  • Faraizah Abdul Karim
    National Blood Centre, Kuala Lumpur, Malaysia.
  • Johnny Mahlangu
    University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South Africa.
  • Claudia Djambas Khayat
    Department of Pediatrics, Hotel Dieu de France Saint Joseph University, Beirut, Lebanon.
  • Jeannie Ong
    Brokenshire Integrated, Davao City, Philippines.
  • Stephanie P'Ng
    Royal Perth Hospital, Perth, WA, Australia.
  • Johannes Oldenburg
    University of Bonn, Bonn, Germany.
  • Cindy Leissinger
    Departments of Medicine, Pediatrics, and Pathology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
  • Samantha Lucas
    CSL Behring, King of Prussia, Pennsylvania, USA.
  • Amy Suen
    CSL Behring, King of Prussia, Pennsylvania, USA.
  • Blanca Salazar
    CSL Behring, King of Prussia, Pennsylvania, USA.
  • Ingrid Pabinger
    Clinical Division of Haematology and Haemostaseology, Department of Medicine, Medical University Vienna, Vienna, Austria.

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