Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease.

Journal: Frontiers in veterinary science
Published Date:

Abstract

INTRODUCTION: Hypoxia-inducible factors (HIF) regulate gene transcription, which aids hypoxia adaptation while promoting renal fibrosis. Non-transferrin-bound iron (NTBI) is a catalytic form of iron that can lead to oxidative damage. However, NTBI in cat biofluids has rarely been evaluated.

Authors

  • Chien-Hui Chen
    School of Veterinary Medicine, College of Bio-Resources and Agriculture, Institute of Veterinary Clinical Science, National Taiwan University, Taipei, Taiwan.
  • Wei-Li Hsu
    College of Veterinary Medicine, Graduate Institute of Microbiology and Public Health, National Chung-Hsing University, Taichung, Taiwan.
  • Pei-Shiue Jason Tsai
    School of Veterinary Medicine, College of Bio-Resources and Agriculture, Institute of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
  • Chun-Fu Lai
    National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
  • Meng-Ting Wu
    Department of Chemistry, College of Science, National Taiwan University, Taipei, Taiwan.
  • Ya-Jane Lee
    School of Veterinary Medicine, College of Bio-Resources and Agriculture, Institute of Veterinary Clinical Science, National Taiwan University, Taipei, Taiwan.

Keywords

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