Artificial intelligence in triage of COVID-19 patients.

Journal: Frontiers in artificial intelligence
Published Date:

Abstract

In 2019, COVID-19 began one of the greatest public health challenges in history, reaching pandemic status the following year. Systems capable of predicting individuals at higher risk of progressing to severe forms of the disease could optimize the allocation and direction of resources. In this work, we evaluated the performance of different Machine Learning algorithms when predicting clinical outcomes of patients hospitalized with COVID-19, using clinical data from hospital admission alone. This data was collected during a prospective, multicenter cohort that followed patients with respiratory syndrome during the pandemic. We aimed to predict which patients would present mild cases of COVID-19 and which would develop severe cases. Severe cases were defined as those requiring access to the Intensive Care Unit, endotracheal intubation, or even progressing to death. The system achieved an accuracy of 80%, with Area Under Receiver Operating Characteristic Curve (AUC) of 91%, Positive Predictive Value of 87% and Negative Predictive Value of 82%. Considering that only data from hospital admission was used, and that this data came from low-cost clinical examination and laboratory testing, the low false positive rate and acceptable accuracy observed shows that it is feasible to implement prediction systems based on artificial intelligence as an effective triage method.

Authors

  • Yuri Oliveira
    School of Medicine, University of Brasilia, Brasilia, Brazil.
  • Iêda Rios
    School of Health Sciences, University of Brasilia, Brasilia, Brazil.
  • Paula Araújo
    University Hospital of Brasilia, University of Brasilia, Brasilia, Brazil.
  • Alinne Macambira
    Hospital of Tropical Diseases, Federal University of Tocantins, Araguaína, Brazil.
  • Marcos Guimarães
    University Hospital, Federal University of Vale do São Francisco, Petrolina, Brazil.
  • Lúcia Sales
    Institute of Health Sciences, Federal University of Pará, Belém, Brazil.
  • Marcos Rosa Júnior
    University Hospital Cassiano Antônio de Moraes, Federal University of Espírito Santo, Vitória, Brazil.
  • André Nicola
    School of Medicine, University of Brasilia, Brasilia, Brazil.
  • Mauro Nakayama
    University Hospital, Federal University of Grande Dourados, Dourados, Brazil.
  • Hermeto Paschoalick
    University Hospital, Federal University of Grande Dourados, Dourados, Brazil.
  • Francisco Nascimento
    Department of Electrical Engineering, University of Brasilia, Brasilia, Brazil.
  • Carlos Castillo-Salgado
    School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
  • Vania Moraes Ferreira
    School of Medicine, University of Brasilia, Brasilia, Brazil.
  • Hervaldo Carvalho
    School of Medicine, University of Brasilia, Brasilia, Brazil.

Keywords

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