Effects of super high-flux vitamin E-coated and medium cut-off dialyzers on uremic toxins removal and biocompatibility: the E-FLUX randomized controlled study.

Journal: Clinical kidney journal
Published Date: Apr 11, 2025

Abstract

BACKGROUND: Medium cut-off hemodialysis (MCO-HD) improves removal of middle molecules (MM) uremic toxins. The effects of the novel super high-flux vitamin E-coated (SHFVE) dialyzer on MM removal and biocompatibility parameters including inflammation and oxidative stress remain to be investigated.

Authors

  • Mohamed Belmouaz
    Department of Nephrology, Poitiers University Hospital, Poitiers, France.
  • Etienne Cogne
    Department of Nephrology, Poitiers University Hospital, Poitiers, France.
  • Florent Joly
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.
  • Fabien Duthe
    Department of Nephrology, Poitiers University Hospital, Poitiers, France.
  • Estelle Desport
    Department of Nephrology, Poitiers University Hospital, Poitiers, France.
  • Cecile Martin
    Department of Nephrology, Poitiers University Hospital, Poitiers, France.
  • Thierry Hauet
    Department of Pharmacology, Poitiers University Hospital, Poitiers, France.
  • Sebastien Giraud
    Institut National de la Sante et de la Recherche Médicale (INSERM) IRMETIST U1313, Poitiers University Hospital, Poitiers, France.
  • Estelle Lemarie
    Institut National de la Sante et de la Recherche Médicale (INSERM) IRMETIST U1313, Poitiers University Hospital, Poitiers, France.
  • Lisa Durocher
    Department of Biostatistics, Centre d'Investigation Clinique CIC 1402, Poitiers University Hospital, Poitiers, France.
  • Frank Bridoux
    Néphrologie, CHU Poitiers, Poitiers, France.

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