Percutaneous Endoscopic Debridement and Drainage as a First-Line Diagnosis and Management Intervention for Spondylodiscitis: A Novel Treatment Algorithm.

Journal: Operative neurosurgery (Hagerstown, Md.)
Published Date: May 9, 2025

Abstract

BACKGROUND AND OBJECTIVES: Spondylodiscitis (SD) is an infection of the intervertebral disk. In the nonseptic, MRI-positive patient without focal deficits, current guidelines recommend computed tomography-guided biopsy (CTGB) for pathogen identification. Yet, pathogen positivity from CTGB is low (37%). Percutaneous endoscopic debridement and drainage (PEDD) may improve pathogen identification and reduce pain. We aimed to evaluate the utility of PEDD as the first-line intervention for the diagnosis and management of SD.

Authors

  • Nischal Acharya
    Department of Neurological Surgery, The University of California, Irvine, Orange, California, USA.
  • Gabrielle Hovis
    The University of California, Irvine School of Medicine, Irvine, California, USA.
  • Ashish Ramesh
    The University of California, Irvine School of Medicine, Irvine, California, USA.
  • Alvin Chan
    Department of Neurological Surgery, The University of California, Irvine, Orange, California, USA.
  • Charles H Li
    Department of Radiology, The University of California, Irvine, Orange, California, USA.
  • Shruti Gohil
    Department of Infectious Disease, The University of California, Irvine, Orange, California, USA.
  • Michael Oh
    Department of Neurological Surgery, The University of California, Irvine, Orange, California, USA.

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