Artemisia extracts and phytochemicals inhibit glutamate-induced oxidative cell death and upregulate the Nrf2/HO-1 signaling pathway in HT22 neuronal cells.

Journal: Journal of ethnopharmacology
Published Date: May 10, 2025

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia (Asteraceae) is a diverse genus of plants with ecological, economic, and therapeutic significance. Some species have been traditionally used for neuroprotection; however, their bioactive potential remains underexplored.

Authors

  • Neil Patrick Uy
    Department of Plant Science and Technology, Chung-Ang University, Anseong, 17546, Republic of Korea. Electronic address: uyneilpatrick@gmail.com.
  • Mei Tong He
    College of Korean Medicine, Gachon University, Seongnam, 13120, Republic of Korea. Electronic address: ellenho@gachon.ac.kr.
  • Chang-Dae Lee
    Department of Plant Science and Technology, Chung-Ang University, Anseong, 17546, Republic of Korea. Electronic address: great7321@naver.com.
  • Yunji Lee
    Department of Herbal Crop Research, National Institute of Horticultural and Herbal Science, Eumseong, 27709, Republic of Korea. Electronic address: yoong0625@korea.kr.
  • Ki Sung Kang
    College of Korean Medicine, Gachon University, Seongnam, Republic of Korea.
  • Sanghyun Lee
    3Department of Integrative Plant Science, Chung-Ang University, Anseong, Gyeonggi 17546 Korea.

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