Identification, characterisation and outcomes of pre-atrial fibrillation in heart failure with reduced ejection fraction.

Journal: ESC heart failure
Published Date: Jun 18, 2025

Abstract

AIMS: Atrial fibrillation (AF) in heart failure with reduced ejection fraction (HFrEF) has prognostic implications. Using a machine learning algorithm (FIND-AF), we aimed to explore clinical events and the cardiac magnetic resonance (CMR) characteristics of the pre-AF phenotype in HFrEF.

Authors

  • Anna Helbitz
    Faculty of Medicine and Health, University of Leeds, Leeds, UK.
  • Ramesh Nadarajah
    Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK.
  • Lan Mu
  • Harriet Larvin
    Wolfson Institute of Population Health, Queen Mary, University of London, London, UK.
  • Hesham Ismail
    Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Ali Wahab
    Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK.
  • Patrick Thompson
    Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
  • Peter Harrison
    Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
  • Mohammad Harris
    Leeds Institute of Data Analytics, University of Leeds, Leeds, UK.
  • Tobin Joseph
    Leeds Institute of Data Analytics, University of Leeds, Leeds, UK.
  • Sven Plein
    From the Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands (Q.T., E.H.M.P., D.P.S., A.d.R., H.J.L., R.J.v.d.G.); Department of Electrical Engineering, Fudan University, Shanghai, China (W.Y., Y.W.); Multidisciplinary Cardiovascular Research Centre & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, England (P.G., S.P.); Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (L.H., L.X.); and Departments of Cardiology (M.S.) and Radiology (J.T.), Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
  • Mark Petrie
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Marco Metra
    Cardiology Department, University of Brescia, Spedali Civili of Brescia, Brescia.
  • Jianhua Wu
  • Peter Swoboda
    Institute for Cardiovascular Science, University College London, United Kingdom
  • Chris P Gale
    Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Keywords

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