Comprehensive analysis of potential biomarkers for the diagnosis and prognosis of Cervical squamous cell carcinoma - based on GEO and TCGA databases.

Journal: Frontiers in oncology
Published Date:

Abstract

BACKGROUND: Cervical squamous cell carcinoma (CESC) constitutes a substantial global health burden, especially in resource-limited regions. The identification of reliable biomarkers is critical for developing a clinically applicable nomogram to predict survival outcomes and evaluate immune infiltration in CESC patients.

Authors

  • Yufen Chen
    Department of Obstetrics and Gynecology, The First Affiliate Hospital of Jinan University, Guangzhou, Guangdong, China.
  • Qinghua Deng
    Center for Radiation Oncology, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310001, China.
  • Tengyue Fu
    Department of Neurosurgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
  • Yuxiang Huang
    Guangdong-Hong Kong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, Guangdong, China.
  • Houlin Li
    Guangdong-Hong Kong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, Guangdong, China.
  • Jingmu Xie
    Guangdong-Hong Kong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, Guangdong, China.
  • Feng Liao
    Department of Orthopaedics, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, 32# W. Sec 2, 1st Ring Rd, Qingyang District, Chengdu, 610072, China. liaofeng@uestc.edu.cn.
  • Feimiao Zeng
    Department of Gynaecology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
  • Xinyi Fang
    Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Ruiman Li
    Department of Gynaecology and Obstetrics, the First Affiliated Hospital of Jinan University, Guangzhou, China.
  • Zhuming Chen
    Guangdong-Hong Kong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, Guangdong, China.

Keywords

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