Machine Learning Radiomics for Predicting Response to MR-Guided Radiotherapy in Unresectable Hepatocellular Carcinoma: A Multicenter Cohort Study.

Journal: Journal of hepatocellular carcinoma
Published Date: Jan 1, 2025

Abstract

BACKGROUND: This study was conducted to assess the efficacy and safety of magnetic resonance (MR)-guided hypofractionated radiotherapy in patients with unresectable hepatocellular carcinoma (HCC). Machine learning-based radiomics was utilized to predict responses in these patients.

Authors

  • Ke Su
    Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Xin Liu
    Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences, Weifang, Shandong, China.
  • Yue-Can Zeng
    Department of Radiation Oncology, Cancer Treatment Center, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570311, People's Republic of China.
  • Junnv Xu
    Department of Medical Oncology, The Second Affiliated Hospital, Hainan Medical University, Haikou, Hainan Province, 570311, People's Republic of China.
  • Han Li
  • Heran Wang
    Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110004, People's Republic of China.
  • Shanshan Du
    Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, 350122, Fujian Province, China.
  • Huadong Wang
    School of Computer Science and Technology, Anhui University, China.
  • Jinbo Yue
    Department of Abdominal Radiotherapy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, People's Republic of China.
  • Yong Yin
    Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong, 250117, China.
  • Zhenjiang Li
    Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China; Shandong Medical Imaging and Radiotherapy Engineering Center (SMIREC), Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.

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