Learning-based multi-material CBCT image reconstruction with ultra-slow kV switching.

Journal: Journal of X-ray science and technology
Published Date:

Abstract

ObjectiveThe purpose of this study is to perform multiple () material decomposition with deep learning method for spectral cone-beam CT (CBCT) imaging based on ultra-slow kV switching.ApproachIn this work, a novel deep neural network called SkV-Net is developed to reconstruct multiple material density images from the ultra-sparse spectral CBCT projections acquired using the ultra-slow kV switching technique. In particular, the SkV-Net has a backbone structure of U-Net, and a multi-head axial attention module is adopted to enlarge the perceptual field. It takes the CT images reconstructed from each kV as input, and output the basis material images automatically based on their energy-dependent attenuation characteristics. Numerical simulations and experimental studies are carried out to evaluate the performance of this new approach.Main ResultsIt is demonstrated that the SkV-Net is able to generate four different material density images, i.e., fat, muscle, bone and iodine, from five spans of kV switched spectral projections. Physical experiments show that the decomposition errors of iodine and CaCl are less than 6, indicating high precision of this novel approach in distinguishing materials.SignificanceSkV-Net provides a promising multi-material decomposition approach for spectral CBCT imaging systems implemented with the ultra-slow kV switching scheme.

Authors

  • Chenchen Ma
    School of Information and Communication Engineering, Dalian University of Technology, Dalian, Liaoning, China.
  • Jiongtao Zhu
    Research Center for Medical Artificial Intelligence, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, People's Republic of China.
  • Xin Zhang
    First Department of Infectious Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China.
  • Han Cui
    Research Center for Medical Artificial Intelligence, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, People's Republic of China.
  • Yuhang Tan
    Shandong Jiaotong University, Jinan, China.
  • Jinchuan Guo
  • Hairong Zheng
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Dong Liang
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Ting Su
    Changsha Jingyi Pharmaceutical Technology Co., Ltd, Changsha, Hunan Province, China.
  • Yi Sun
    Department of Environmental and Occupational Health, Program in Public Health, University of California, Irvine, CA, USA.
  • Yongshuai Ge
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

Keywords

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