Artificial Intelligence-Derived Electrocardiographic Age Predicts Mortality in Adults With Congenital Heart Disease.

Journal: JACC. Advances
Published Date: May 14, 2025

Abstract

BACKGROUND: Artificial intelligence (AI) can be used to estimate age from the electrocardiogram (AI-ECG age). The difference between AI-ECG age and chronological age (delta-age) is an independent predictor of mortality in the general population.

Authors

  • Scott Anjewierden
    Department of Pediatrics and Adolescent Medicine Mayo Clinic Rochester MN USA.
  • Donnchadh O'Sullivan
    Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minn.
  • Kathryn E Mangold
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Itzhak Zachi Attia
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Francisco Lopez-Jimenez
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Paul A Friedman
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Alexander C Egbe
    Division of Structural Heart Disease, Mayo Clinic, Rochester, Minn.
  • Heidi M Connolly
    Depertment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  • William R Miranda
    Depertment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  • Samuel J Asirvatham
    Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
  • Jennifer Dugan
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, MN.
  • Katia Bravo-Jaimes
    Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
  • Talha Niaz
    Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester MN USA.
  • Malini Madhavan
    Department of Cardiovascular Medicine Mayo Clinic Rochester MN USA.
  • Luke J Burchill
    Division of Structural Heart Disease, Mayo Clinic, Rochester, Minn. Electronic address: burchill.luke@mayo.edu.

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