Closing the diagnostic gap: A narrative review of recent advances in functional MRI diagnostics in spinal cord injury.

Journal: Brain & spine
Published Date: Jan 1, 2025

Abstract

INTRODUCTION: Conventional MRI (T1 and T2-weighted sequences) is the standard for diagnosing spinal cord injuries but often lacks specificity, showing limited correlation with microstructural changes and function. This creates a diagnostic gap, especially in patients with mild or ambiguous symptoms, delaying early intervention.

Authors

  • Christian J Entenmann
    Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Neurosurgery, Berlin, Germany.
  • Katharina Kersting
    Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Neurosurgery, Berlin, Germany.
  • Peter Vajkoczy
    Department of Neurosurgery and Center for Stroke research Berlin (CSB), Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Charité CyberKnife Center, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Anna Zdunczyk
    Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Neurosurgery, Berlin, Germany.

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