Longitudinal changes in body composition during palliative systemic chemotherapy and survival outcomes in metastatic colorectal cancer.

Journal: World journal of gastrointestinal oncology
Published Date: May 15, 2025

Abstract

BACKGROUND: In patients with metastatic colorectal cancer, chemotherapy may lead to changes in body composition, including skeletal muscle quantity and quality, and body fat area and distribution. Longitudinal follow-up data in a homogeneous population are required to understand these changes better.

Authors

  • Hyehyun Jeong
    Department of Oncology, Asan Medical Center, Seoul 05505, South Korea.
  • Yousun Ko
    Biomedical Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.
  • Kyung Won Kim
    Department of Pediatrics, Severance Children's Hospital, Institute of Allergy, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. kwkim@yuhs.ac.
  • Ji Sung Lee
    Clinical Research Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. (J.S.L.).
  • Seyoung Seo
    Department of Oncology, Asan Medical Center, Seoul 05505, South Korea.
  • Sun Young Kim
    School of Mechanical Engineering, Kunsan National University, Gunsan-si 54150, Republic of Korea.
  • Yong Sang Hong
    Department of Oncology, Asan Medical Center, Seoul 05505, South Korea.
  • Jeong Eun Kim
    Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • Tae Won Kim
    AI‧Future Strategy Center, National Information Society Agency of Korea, Daegu, Korea.

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