Enterotype-stratified gut microbial signatures in MASLD and cirrhosis based on integrated microbiome data.

Journal: Frontiers in microbiology
Published Date: Jan 1, 2025

Abstract

INTRODUCTION: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health challenge, characterized by significant variability in progression and clinical outcomes. While the gut microbiome is increasingly recognized as a key factor in liver disease development, its role in disease progression and associated mechanisms remains unclear. This study systematically investigated the gut microbiota's role in MASLD and liver cirrhosis progression, focusing on individual bacterial strains, microbial community dynamics, and functional characteristics across different enterotypes.

Authors

  • Heng Yuan
    Department of Bioconvergence, Hoseo University, Asan 31499, Korea.
  • Junyu Zhou
    Department of Bioconvergence, Hoseo University, Asan 31499, Korea.
  • Xuangao Wu
    Department of Bioconvergence, Hoseo University, Asan, Republic of Korea.
  • Shiwei Wang
    PTN Graduate Program, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, PR China.
  • Sunmin Park
    Department of Bioconvergence, Hoseo University, Asan 31499, Korea.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals