Prediction of Poor Visual Outcomes at Idiopathic Intracranial Hypertension Diagnosis Using a Supervised Machine Learning Algorithm.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
Published Date: May 15, 2025

Abstract

BACKGROUND: Idiopathic intracranial hypertension (IIH) is a vision-threatening disorder mainly affecting women of a reproductive age. Prompt diagnosis and intervention are vital to prevent vision loss, but validated tools to predict visual outcomes are lacking. The purpose of this study was to create a machine learning algorithm predicting poor visual outcomes at the time that the diagnosis of IIH is established, and stratifying risk among those with and without poor visual acuity at presentation.

Authors

  • Jacqueline K Shaia
    Department of Population and Quantitative Health Sciences (JKS, NKS), Case Western Reserve University, Cleveland, Ohio; Case Western Reserve School of Medicine (JKS, TAA, IPT, JRR, JYC), Cleveland, Ohio; Center for Ophthalmic Bioinformatics (JKS, RPS, KET), Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio; School of Nursing, Case Western Reserve University (NKS), Cleveland, Ohio; Cleveland Clinic Cole Eye Institute (RPS, KET, DAC), Cleveland, Ohio; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (RPS, KET, DAC), Cleveland, Ohio; and Cleveland Clinic Martin Hospitals (RPS), Cleveland Clinic, Florida.
  • Taseen A Alam
  • Ilene P Trinh
  • Jenna R Rock
  • Jeffrey Y Chu
  • Nicholas K Schiltz
    *Department of Epidemiology & Biostatistics, Case Western Reserve University School of Medicine, Cleveland, OH †Department of Sociology, University of Nebraska-Lincoln, Lincoln, NE ‡Department of Health Policy and Management, George Washington University Milken Institute School of Public Health, Washington, DC §Department of Family Medicine, Michigan State University, East Lansing, MI ∥Department of Family Medicine and Community Health, Case Western Reserve University School of Medicine, Cleveland, OH.
  • Rishi P Singh
    Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Katherine E Talcott
  • Devon A Cohen

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