Multi-Steroid Profiling and Machine Learning Reveal Androgens as Candidate Biomarkers for Endometrial Cancer Diagnosis: A Case-Control Study.

Journal: Cancers
Published Date: May 16, 2025

Abstract

OBJECTIVE: To evaluate the diagnostic and prognostic potential of preoperative serum steroid levels in endometrial cancer (EC) alone and in combination with clinical parameters and biomarkers CA-125 and HE4.

Authors

  • Marija Gjorgoska
    Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
  • Angela E Taylor
    Institute of Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK.
  • Špela Smrkolj
    Department of Gynecology and Obstetrics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
  • Tea Lanišnik Rižner
    Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.

Keywords

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