Fair ultrasound diagnosis via adversarial protected attribute aware perturbations on latent embeddings.

Journal: NPJ digital medicine
Published Date:

Abstract

Deep learning techniques have significantly enhanced the convenience and precision of ultrasound image diagnosis, particularly in the crucial step of lesion segmentation. However, recent studies reveal that both train-from-scratch models and pre-trained models often exhibit performance disparities across sex and age attributes, leading to biased diagnoses for different subgroups. In this paper, we propose APPLE, a novel approach designed to mitigate unfairness without altering the parameters of the base model. APPLE achieves this by learning fair perturbations in the latent space through a generative adversarial network. Extensive experiments on both a publicly available dataset and an in-house ultrasound image dataset demonstrate that our method improves segmentation and diagnostic fairness across all sensitive attributes and various backbone architectures compared to the base models. Through this study, we aim to highlight the critical importance of fairness in medical segmentation and contribute to the development of a more equitable healthcare system.

Authors

  • Zikang Xu
    College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China; MOE Key Laboratory of Pollution Processes and Environmental Criteria, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, Nankai University, Tianjin, 300350, China.
  • Fenghe Tang
    School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, Anhui, China.
  • Quan Quan
    School of Computer Science and Engineering, Central South University, Changsha, 410083, People's Republic of China.
  • Qingsong Yao
    Institute of Computing Technology, Chinese Academy of Sciences (CAS), Beijing, 100080, China; University of Chinese Academy of Sciences (UCAS), Beijing, 101408, China.
  • Qingpeng Kong
    School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, Anhui, China.
  • Jianrui Ding
  • Chunping Ning
    Department of Ultrasound, the Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: 152081340@qq.com.
  • S Kevin Zhou

Keywords

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