A comparative analysis of dengue, chikungunya, and Zika in a pediatric cohort over 18 years.

Journal: medRxiv : the preprint server for health sciences
Published Date: May 17, 2025

Abstract

BACKGROUND: Dengue, chikungunya, and Zika are diseases of major human concern. Differential diagnosis is complicated in children and adolescents by their overlapping clinical features (signs, symptoms, and complete blood count results). Few studies have directly compared the three diseases. We aimed to identify distinguishing pediatric characteristics of each disease.

Authors

  • Fausto Andres Bustos Carrillo
    Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, USA.
  • Sergio Ojeda
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Nery Sanchez
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Miguel Plazaola
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Damaris Collado
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Tatiana Miranda
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Saira Saborio
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Brenda Lopez Mercado
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Jairo Carey Monterrey
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Sonia Arguello
    Sustainable Sciences Institute, Managua, Nicaragua.
  • Lora Campredon
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Zijin Chu
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Colin J Carlson
    Department of Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, CT, USA.
  • Aubree Gordon
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Angel Balmaseda
    Laboratorio Nacional de Virología, Centro Nacional de Diagnóstico y Referencia, Ministry of Health, Managua, Nicaragua.
  • Guillermina Kuan
    Centro de Salud Sócrates Flores Vivas, Ministry of Health, Managua, Nicaragua.
  • Eva Harris
    Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, 94720-3370, USA.

Keywords

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