Prognostic effect of CD74 and development of a radiomic model for predicting CD74 expression in non-small cell lung cancer.

Journal: Frontiers in medicine
Published Date: May 21, 2025

Abstract

BACKGROUND: The classical prognostic indicators of lung cancer are no longer sufficient for prognostic stratification and individualized treatment of highly heterogeneous non-small cell lung cancer (NSCLC). This study aimed to establish a radiomics model to predict CD74 expression level in NSCLC patients and to explore its role in the tumor immune response and its prognostic value.

Authors

  • Yancheng Wang
    State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou 310027, China. yanchwang@zju.edu.cn.
  • Zhen Gao
    Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Meng Li
    Co-Innovation Center for the Sustainable Forestry in Southern China; Cerasus Research Center; College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.
  • Zhen Feng
    Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Hui Wang
    Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Keywords

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