Evaluation of Fourier-Transform Infrared Spectroscopy with IR Biotyper system for Streptococcus pneumoniae serotyping.
Journal:
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Published Date:
May 21, 2025
Abstract
PURPOSE: Streptococcus pneumoniae is an important human pathogen and its virulence is centered on the expression of a polysaccharide capsule. Serotyping pneumococci has clinical and epidemiological relevance. As the gold standard (Quellung reaction) is expensive and somehow laborious, alternative methodologies for timely serotyping are desirable. We aimed to evaluate IR Biotyper (Bruker), which is based on FT-IRS, as a tool for serotyping S. pneumoniae by customizing a classifier focusing on PCV15 serotypes.
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