An X-ray bone age assessment method for hands and wrists of adolescents in Western China based on feature fusion deep learning models.

Journal: International journal of legal medicine
Published Date:

Abstract

The epiphyses of the hand and wrist serve as crucial indicators for assessing skeletal maturity in adolescents. This study aimed to develop a deep learning (DL) model for bone age (BA) assessment using hand and wrist X-ray images, addressing the challenge of classifying BA in adolescents. The results of this DL-based classification were then compared and analyzed with those obtained from manual assessment. A retrospective analysis was conducted on 688 hand and wrist X-ray images of adolescents aged 11.00-23.99 years from western China, which were randomly divided into training set, validation set and test set. The BA assessment results were initially analyzed and compared using four DL network models: InceptionV3, InceptionV3 + SE + Sex, InceptionV3 + Bilinear and InceptionV3 + Bilinear. + SE + Sex, to identify the DL model with the best classification performance. Subsequently, the results of the top-performing model were compared with those of manual classification. The study findings revealed that the InceptionV3 + Bilinear + SE + Sex model exhibited the best performance, achieving classification accuracies of 96.15% and 90.48% for the training and test set, respectively. Furthermore, based on the InceptionV3 + Bilinear + SE + Sex model, classification accuracies were calculated for four age groups (< 14.0 years, 14.0 years ≤ age < 16.0 years, 16.0 years ≤ age < 18.0 years, ≥ 18.0 years), with notable accuracies of 100% for the age groups 16.0 years ≤ age < 18.0 years and ≥ 18.0 years. The BA classification, utilizing the feature fusion DL network model, holds significant reference value for determining the age of criminal responsibility of adolescents, particularly at the critical legal age boundaries of 14.0, 16.0, and 18.0 years.

Authors

  • Ya-Hui Wang
    Institute of Forensic Science, Ministry of Justice, China, Shanghai Key Laboratory of Forensic Medicine, NO1347, West Guangfu Road, Putuo District, Shanghai, China.
  • Hui-Ming Zhou
    Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.
  • Lei Wan
    Institute of Forensic Science, Ministry of Justice, China, Shanghai Key Laboratory of Forensic Medicine, NO1347, West Guangfu Road, Putuo District, Shanghai, China.
  • Yu-Cheng Guo
    Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, 98 XiWu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
  • Yuan-Zhe Li
    Department of CT/MRI, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
  • Tai-Ang Liu
    School of Materials Science and Engineering, Shanghai University, NO99, Shangda Road, Baoshan District, Shanghai, China.
  • Jian-Xin Guo
    College of Forensic Medicine, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, PR China.
  • Dan-Yang Li
    School of Computer Science and Engineering, South China University of Technology, Guangzhou 510006, China.
  • Teng Chen
    College of Medicine and Forensics, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710004, Shaanxi, People's Republic of China.

Keywords

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