Impact of hyperglycaemia on cellular microenvironment and function of endometrium and uterine tube: scoping review focused on infertility in diabetic women.

Journal: Frontiers in cell and developmental biology
Published Date: May 23, 2025

Abstract

INTRODUCTION: Diabetes mellitus (DM) and associated comorbidities correspond to female infertility by many interrelated mechanisms. Yet most prior research focuses only on ovary dysfunction. Our work evaluates literature mechanisms of DM-induced uterine tube and endometrial dysfunction, corresponding impacts on female fertility, and potential evidence-based intervention targets.

Authors

  • Peter Jackuliak
    Fifth Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital Bratislava, Bratislava, Slovakia.
  • Martin Jankovský
    Fifth Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital Bratislava, Bratislava, Slovakia.
  • Magdaléna Kovářová
    Fifth Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital Bratislava, Bratislava, Slovakia.
  • Jaroslav Voller
    Faculty of Healthcare Studies, University of Western Bohemia, Pilsen, Czechia.
  • Claudia Feitscherová
    Institute of Histology and Embryology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
  • Ivan Varga
    Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, 81372 Bratislava, Slovakia.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals