End-to-end prognostication in pancreatic cancer by multimodal deep learning: a retrospective, multicenter study.

Journal: European radiology
Published Date:

Abstract

OBJECTIVES: Pancreatic cancer treatment plans involving surgery and/or chemotherapy are highly dependent on disease stage. However, current staging systems are ineffective and poorly correlated with survival outcomes. We investigate how artificial intelligence (AI) can enhance prognostic accuracy in pancreatic cancer by integrating multiple data sources.

Authors

  • Megan Schuurmans
    Diagnostic Image Analysis Group, Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Anindo Saha
    Diagnostic Image Analysis Group, Department of Medical Imaging, Radboudumc, Nijmegen, The Netherlands.
  • Natália Alves
    Diagnostic Imaging Analysis Group, Medical Imaging Department, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands.
  • Pierpaolo Vendittelli
    Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Derya Yakar
    Department of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address: d.yakar@umcg.nl.
  • Sergio Sabroso-Lasa
    Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center, Madrid, Spain.
  • Nannan Xue
    Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center, Madrid, Spain.
  • Núria Malats
    Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center, Madrid, Spain.
  • Henkjan Huisman
    Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
  • John Hermans
    Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Geert Litjens
    Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.

Keywords

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