A Personalized Closed-Loop Brain Stimulation Protocol for Difficulty Falling Asleep.

Journal: IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Published Date: May 23, 2025

Abstract

BACKGROUND: Insomnia, a common mental health issue, is characterized by brain hyperarousal and difficulties in transitioning between sleep stages. Pharmacological interventions often come with adverse effects and variable efficacy, while non-invasive brain stimulation holds potential but lacks in providing tailored, dynamic, and precisely targeted solutions.

Authors

  • Lin Wang
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.
  • Yue Yu
    Department of Mathematics, Lehigh University, Bethlehem, PA, USA.
  • Shaofei Ying
  • Mingju Wang
  • Yun Qin
    National Climate Center, Chinese Meteorological Administration, Beijing 100081, China.
  • Tiejun Liu
    Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China; Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu, 610054, China.
  • DeZhong Yao
    The Key Laboratory for Neuro Information of Ministry of Education, Center for Information in Bio Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.

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