Occurrence, Sources, and Prioritization of Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging PFASs.

Journal: Molecules (Basel, Switzerland)
Published Date: May 25, 2025

Abstract

As regulations ban legacy PFASs, many emerging PFASs are being developed, leading to their release into the aquatic environment and drinking water. However, research studies on these emerging PFASs in drinking water are limited, and current standards only cover a few legacy PFASs, leaving many emerging PFASs unregulated and their toxicity unknown. Therefore, a machine learning-based suspect screening combined with target screening was employed to comprehensively identify and quantify both legacy and novel PFASs in drinking water from the Yangtze River Delta, and their potential sources of contamination were determined through pollutant profile analysis. A total of 30 PFASs were identified, including 16 legacy and 14 novel PFASs, categorized into 11 classes. Quantitative and semi-quantitative analyses revealed that the maximum concentrations of 30 PFASs ranged from

Authors

  • Zixin Qian
    Shanghai Municipal Center for Disease Control and Prevention/State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China; School of Public Health, Fudan University, Shanghai 200032, China.
  • Chao Feng
    Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
  • Yuhang Chen
    School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China,People's Republic of China.
  • Yuanjie Lin
    School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
  • Ziwei Liang
    Shanghai Municipal Center for Disease Control and Prevention, State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China.
  • Hailei Qian
    Shanghai Municipal Center for Disease Control and Prevention, State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China.
  • Jingxian Zhou
    Shanghai Municipal Center for Disease Control and Prevention, State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China.
  • Jinjing Ma
    Shanghai Municipal Center for Disease Control and Prevention, State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China.
  • Yue Jin
    Department of Biomedical Engineering, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.
  • Dasheng Lu
    Shanghai Municipal Center for Disease Control and Prevention/State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China.
  • Guoquan Wang
    Shanghai Municipal Center for Disease Control and Prevention/State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai 200336, China. Electronic address: wangguoquan@scdc.sh.cn.
  • Ping Xiao
    Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine,National Administration of Traditional Chinese Medicine Key Laboratory of Chinese Medicinal Resources Recycling Utilization, Nanjing University of Chinese Medicine Nanjing 210023, China.
  • Zhijun Zhou
    Institute of Electrical Engineering, School of Automation, Hangzhou Dianzi University, Hangzhou, People's Republic of China.

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