A novel network architecture for post-applicator placement CT auto-contouring in cervical cancer HDR brachytherapy.

Journal: Medical physics
Published Date: May 25, 2025

Abstract

BACKGROUND: High-dose-rate brachytherapy (HDR-BT) is an integral part of treatment for locally advanced cervical cancer, requiring accurate segmentation of the high-risk clinical target volume (HR-CTV) and organs at risk (OARs) on post-applicator CT (pCT) for precise and safe dose delivery. Manual contouring, however, is time-consuming and highly variable, with challenges heightened in cervical HDR-BT due to complex anatomy and low tissue contrast. An effective auto-contouring solution could significantly enhance efficiency, consistency, and accuracy in cervical HDR-BT planning.

Authors

  • Yang Lei
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322.
  • Ming Chao
    Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kaida Yang
    Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Vishal Gupta
    Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai Medical School, New York, New York.
  • Emi J Yoshida
    Department of Radiation Oncology, University of California at San Francisco, San Francisco, California, USA.
  • Tingyu Wang
  • Xiaofeng Yang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
  • Tian Liu
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

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