Comparative performance analysis of global and chinese-domain large language models for myopia.

Journal: Eye (London, England)
Published Date: Apr 13, 2025

Abstract

BACKGROUND: The performance of global large language models (LLMs), trained largely on Western data, for disease in other settings and languages is unknown. Taking myopia as an illustration, we evaluated the global versus Chinese-domain LLMs in addressing Chinese-specific myopia-related questions.

Authors

  • Zehua Jiang
    Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Yueyuan Xu
    Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Zhi Wei Lim
    Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Ziyao Wang
    Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
  • Yingxiang Han
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Samantha Min Er Yew
    Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Zhe Pan
    Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Qian Wang
    Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
  • Gangyue Wu
    Jinhua Eye Hospital, Jinhua, Zhejiang, China.
  • Tien Yin Wong
    Singapore National Eye Center, Duke-National University of Singapore Medical School, Singapore 168751, Singapore; National Institutes of Health Research Biomedical Research Centre Biomedical Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
  • Xiaofei Wang
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Yaxing Wang
    Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China. yaxingw@gmail.com.
  • Yih Chung Tham
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. thamyc@nus.edu.sg.

Keywords

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