Identification and validation of hypoxia-associated genes positively correlated with in pulmonary adenocarcinoma.

Journal: Translational cancer research
Published Date: May 30, 2025

Abstract

BACKGROUND: Hypoxia contributes to the proliferation, migration, and chemotherapy resistance of lung adenocarcinoma (LUAD). This study aimed to identify hypoxia-related genes (HRGs) in LUAD that were positively correlated with hypoxia-inducible factor 1 alpha (), to advance the diagnosis and treatment of this specific type of cancer.

Authors

  • Haifeng Zhu
  • Yun Wang
    Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
  • Zunyu Chen
    Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
  • Ruonan Guo
    Central Laboratory, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
  • Xiaobai Wu
    Central Laboratory, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
  • Yifan Jiang
  • Yang Shu
    Department of Laboratory Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Hanpeng Huang
    Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Keywords

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