Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models.

Journal: Frontiers in oncology
Published Date: May 27, 2025

Abstract

OBJECTIVE: Molecular biomarkers have the potential to improve the current state of early screening of lung cancer. This investigation aimed to identify novel protein markers for early-stage lung cancer and combine them with traditional tumor markers to develop machine learning models for lung cancer screening.

Authors

  • Huijie Yuan
    College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
  • Shuyin Duan
    College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
  • Clement Yaw Effah
    College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Sitian He
    College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Yaru Chai
    College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Xia Liu
    Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou 571010, People's Republic of China; Key Laboratory of Monitoring and Control of Tropical Agricultural and Forest Invasive Alien Pests, Ministry of Agriculture, Haikou 571010, People's Republic of China.
  • Lihua Ding
    College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Yongjun Wu
    Department of Health Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China. wuyongjun@zzu.edu.cn.

Keywords

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