Creatine kinase in prostate cancer: A biosensor-driven diagnostic paradigm.

Journal: Clinica chimica acta; international journal of clinical chemistry
Published Date:

Abstract

BACKGROUND: Prostate cancer (PC) remains a leading cause of cancer-related morbidity in men worldwide. Emerging evidence suggests that the brain-type creatine kinase isoenzyme (CK-BB) is overexpressed in PC tissue and correlates with tumor progression. However, conventional assays for CK-BB lack the sensitivity and rapid turnaround required for routine clinical use.

Authors

  • Surya Nath Pandey
    Department of Pharmacology, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad 244001 Uttar Pradesh, India.
  • Ehssan Moglad
    Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, 11942, Alkharj, Saudi Arabia.
  • Gaurav Gupta
    Department of Neurosurgery, Rutgers New Jersey Medical School, Newark, New Jersey.
  • H Malathi
    Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
  • Laxmidhar Maharana
    Department of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India.
  • Sami I Alzarea
    Department of Pharmacology, College of Pharmacy, Jouf University, 72341, Aljouf, Sakaka, Saudi Arabia.
  • Imran Kazmi
    Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
  • Abida Khan
    Center For Health Research, Northern Border University, Arar 73213, Saudi Arabia. Electronic address: abeda.mohammed@nbu.edu.sa.

Keywords

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