Single-Cell and Transcriptome Analysis of Periodontitis: Molecular Subtypes and Biomarkers Linked to Mitochondrial Dysfunction and Immunity.

Journal: Journal of inflammation research
Published Date: Dec 27, 2024

Abstract

BACKGROUND: Periodontitis represents an inflammatory disease with multiple contributing factors, affecting both oral and systemic health. The mechanisms linking mitochondrial dysfunction to immune responses in periodontitis remain unclear, limiting the development of individualized diagnostic and therapeutic approaches.

Authors

  • Sijia Ma
    Department of Periodontology, Kunming Medical University School and Hospital of Stomatology, Kunming, 650106, People's Republic of China.
  • Hongbing He
    Department of Periodontology, Kunming Medical University School and Hospital of Stomatology, Kunming, 650106, People's Republic of China.
  • Xiaobin Ren
    Department of Periodontology, Kunming Medical University School and Hospital of Stomatology, Kunming, 650106, People's Republic of China.

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