Prediction of hematogenous metastasis risk from molecular classification in gastric cancer.

Journal: International journal of surgery (London, England)
Published Date: May 28, 2025

Abstract

BACKGROUND: Hematogenous metastasis (HM) poses a significant challenge in the treatment and outcome of gastric cancer (GC). This study identified and characterized molecular subtypes of GC associated with HM to develop predictive models and enhance precision medicine.

Authors

  • Seungho Lee
    Yonsei-Dongsung Photodynamic Therapy Research Center, Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, South Korea.
  • Jaeun Yoo
    Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
  • Seungbok Lee
    Department of Genomic Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  • Sujin Oh
    Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Hyun Myong Kim
    Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
  • Kyoungyun Jeong
    Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
  • Yie-Ri Yoo
    Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
  • Ji-Yeon Shin
    Department of Preventive Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. jyshin@knu.ac.kr.
  • Hye Seung Lee
    Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Kyoung Un Park
    Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
  • Seong-Ho Kong
  • Do Joong Park
    Department of Surgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-shi, Kyeonggi-do, 463-707, South Korea.
  • Hyuk-Joon Lee
  • Han-Kwang Yang

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