Machine learning approaches for cardiovascular disease prediction: A review.

Journal: Archives of cardiovascular diseases
Published Date: May 29, 2025

Abstract

Cardiovascular disease is a leading cause of death worldwide and is associated with significant morbidity and mortality. The use of artificial intelligence techniques, particularly machine learning algorithms, has emerged as a transformative approach for enhancing early diagnostic accuracy of disease compared with conventional diagnostic methods. This systematic review examines three core aspects: (1) comparative analysis of current machine learning algorithms in early diagnosis of cardiovascular disease, (2) operational frameworks for clinical implementation, and (3) critical evaluation of regulatory compliance and ethical implications. It summarizes recent advancements in machine learning-based heart disease prediction, outlines a typical workflow for applying machine learning in clinical settings, and discusses the regulatory and ethical challenges associated with its implementation. Finally, this review explores potential directions for future research in this rapidly evolving field.

Authors

  • Siming Wan
    Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006 Nanchang, China; Jiangxi Provincial Key Laboratory of Intelligent Medical Imaging, 330006 Nanchang, China; Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Taipa, Macau, China.
  • Feng Wan
  • Xi-Jian Dai
    Department of Radiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Minde Road No. 1, Nanchang 330006, Jiangxi Province, China; Jiangxi Provincial Key Laboratory of Intelligent Medical Imaging, Nanchang 330006, Jiangxi Province, China. Electronic address: daixjdoctor@126.com.

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