Macrophage histone lactylation in atherosclerosis progression: mechanisms, predictive models, and therapeutic potential of Ruan Jian Qing Mai formula.

Journal: Life sciences
Published Date:

Abstract

AIMS: This study investigates the role of macrophage histone lactylation-a protein modification-in atherosclerosis progression, particularly in peripheral artery disease (PAD), and evaluates the therapeutic potential of the herbal formula Ruan Jian Qing Mai (RJQM).

Authors

  • Zhi-Qiang Liang
    Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
  • Wang-Sheng Luo
    Department of Cardiology, the First Affiliated Hospital of University of South China, Hengyang, China.
  • Chen-Chen Tang
    Department of Experimental Management, School of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Yi-Lang Zhong
    Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
  • Chen-Qin Xu
    Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
  • Chao Ma
  • Cheng-Lin Jia
    Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
  • Tong-Kai Cai
    Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
  • Yong-Bing Cao
  • Ji Li
    Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, 801 NE 13th Street, CHB 203, Oklahoma City, OK 73104, x 30126.
  • Jian Chen
    School of Pharmacy, Shanghai Jiaotong University, Shanghai, China.

Keywords

No keywords available for this article.