Estimating the Risk of Lower Extremity Complications in Adults Newly Diagnosed With Diabetic Polyneuropathy: Retrospective Cohort Study.

Journal: JMIR diabetes
Published Date: May 29, 2025

Abstract

BACKGROUND: Diabetes-related lower extremity complications, such as foot ulceration and amputation, are on the rise, currently affecting nearly 131 million people worldwide. Methods for early detection of individuals at high risk remain elusive. While data-driven diabetic polyneuropathy algorithms exist, high-performing, clinically useful tools to assess risk are needed to improve clinical care.

Authors

  • Alyce S Adams
    Departments of Health Policy and of Epidemiology and Population Health, School of Medicine, Stanford University, Encina Commons, 615 Crothers Way, Stanford, CA, 94305, United States, 1 6507247555.
  • Catherine Lee
    Systems Research Initiative, Division of Research, Kaiser Permanente, Oakland, CA.
  • Gabriel Escobar
    Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.
  • Elizabeth A Bayliss
    Department of Family Medicine, University of Colorado School of Medicine, Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO, United States.
  • Brian Callaghan
    Department of Neurology, School of Medicine, University of Michigan, Ann Arbor, MI, United States.
  • Michael Horberg
    Mid-Atlantic Permanente Research Institute, Washington DC, MD, United States.
  • Julie A Schmittdiel
  • Connie Trinacty
    The Queen's Medical Center, Honolulu, HI, United States.
  • Lisa K Gilliam
    Kaiser Permanente South San Francisco, South San Francisco, CA, United States.
  • Eileen Kim
    Kaiser Permanente Oakland Medical Center, Oakland, CA, United States.
  • Nima S Hejazi
    Divisions of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, California, USA.
  • Lin Ma
    Department of Radiation Oncology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, United States.
  • Romain Neugebauer

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