To explore the molecular mechanisms and shared genetic characteristics of rheumatoid arthritis and cervical cancer based on multiple omics and clinical samples.

Journal: Discover oncology
Published Date: May 29, 2025

Abstract

OBJECTIVE: The potential association between rheumatoid arthritis (RA) and cervical cancer risk is still debated and necessitates additional clinical investigations. This study aimed to explore this relationship using Mendelian randomization and multi-omics analysis, aiming to enhance insights and reduce redundancy.

Authors

  • Xifeng Xu
    Nanning Second People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, China.
  • Yujie Huang
    Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Wu Wei
    Guangxi Zhuang Autonomous Region People's Hospital, Nanning, China.
  • Zhong Lin
    Faculty of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang, 524088, PR China.
  • Yongjin Luo
    Nanning Second People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, China. luoyongjin951022@163.com.
  • Kaiyi Meng
    Nanning Second People's Hospital, The Third Affiliated Hospital of Guangxi Medical University, Nanning, China. mengkaiyi19830224@163.com.

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