Can large language models fully automate or partially assist paper selection in systematic reviews?

Journal: The British journal of ophthalmology
Published Date: Apr 21, 2025

Abstract

BACKGROUND/AIMS: Large language models (LLMs) have substantial potential to enhance the efficiency of academic research. The accuracy and performance of LLMs in a systematic review, a core part of evidence building, has yet to be studied in detail.

Authors

  • Haichao Chen
    Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Zehua Jiang
    Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Xinyu Liu
    Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
  • Can Can Xue
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Samantha Min Er Yew
    Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Bin Sheng
    MOE Key Laboratory of AI, School of Electronic, Information, and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Ying-Feng Zheng
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Xiaofei Wang
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • You Wu
    Tsinghua University School of Medicine, Beijing, China.
  • Sobha Sivaprasad
    Moorfields Eye Hospital City Road Campus, London, UK.
  • Tien Yin Wong
    Singapore National Eye Center, Duke-National University of Singapore Medical School, Singapore 168751, Singapore; National Institutes of Health Research Biomedical Research Centre Biomedical Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
  • Varun Chaudhary
    Department of Surgery, Division of Ophthalmology, McMaster University, Hamilton, Ontario, Canada.
  • Yih Chung Tham
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. thamyc@nus.edu.sg.

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