Identification and validation of aging related genes in osteoarthritis.

Journal: Frontiers in genetics
Published Date: May 30, 2025

Abstract

BACKGROUND: Osteoarthritis (OA) is a degenerative disease associated with aging. Although an increasing body of research suggests a close relationship between aging and OA, the underlying mechanisms remain unclear. This study explores the relationship between aging related genes (ARGs) and OA, providing potential new targets for understanding the pathogenesis and treatment of OA.

Authors

  • Jian Du
    Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
  • Tian Zhou
    Jingtai Technology Co. Ltd Floor 4, No. 9, Yifenghua Industrial Zone, 91 Huaning Road, Longhua District Shenzhen Guangdong Province 518109 China.
  • Yanghui Dong
    Hebei North University, Zhangjiakou, China.
  • Yunchao Sun
    Hebei North University, Zhangjiakou, China.
  • Wei Peng
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States.

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