Machine Learning-Based Rupture Risk Prediction for Intracranial Aneurysms: A Systematic Review and Meta-Analysis.

Journal: Neurosurgery
Published Date: May 30, 2025

Abstract

BACKGROUND AND OBJECTIVES: Aneurysm risk prediction remains an imprecise science that places patients at risk for either over or undertreatment. Machine learning (ML) models may improve clinical practice by adding precision to risk assessment. This study aims to comprehensively assess the current landscape of ML applications in predicting the risk of aneurysm rupture and compare the performance with the widely used PHASES score.

Authors

  • S Farzad Maroufi
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Maria José Pachón-Londoño
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Maged Ghoche
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Brandon A Nguyen
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Evelyn L Turcotte
    Mayo Clinic Alix School of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
  • Zhen Wang
    Department of Otolaryngology, Longgang Otolaryngology hospital & Shenzhen Key Laboratory of Otolaryngology, Shenzhen Institute of Otolaryngology, Shenzhen, Guangdong, China.
  • Devi P Patra
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Vita Olson
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Brooke S Halpin
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Abhijith R Bathini
    Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.
  • Jenna H Meyer
    Department of Neurological Surgery, Mayo Clinic, Phoenix, Arizona, USA.
  • Chandan Krishna
    Department of Neurosurgery, Mayo Clinic Arizona, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA.
  • Fady T Charbel
    Department of Neurosurgery, University of Illinois Chicago, Chicago, Illinois, USA.
  • Jacques J Morcos
    Department of Neurological Surgery, UTHealth Houston Neuroscience, Houston, Texas, USA.
  • H Hunt Batjer
    Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA.
  • Bernard R Bendok
    Department of Neurosurgery, Mayo Clinic Arizona, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA.

Keywords

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