Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection.

Journal: The EPMA journal
Published Date: Mar 5, 2025

Abstract

BACKGROUND/AIMS: Early recognition of eyelid morphological abnormalities was crucial, as untreated conditions could lead to blinding complications. An eyelid screening system that could provide both anatomical and pathological information was essential for formulating personalized treatment strategies. This study aimed to develop a clinically concerns-based framework capable of identifying common eyelid diseases requiring further intervention by evaluating individual anatomical and pathological changes. This approach would enhance individualized and efficient prevention, while supporting targeted treatment strategies.

Authors

  • Jing Cao
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, People's Republic of China.
  • Kun You
    Merchant Marine College, Shanghai Maritime University, Shanghai 201306, China; Mechanical and Electrical Engineering, Yantai Gold College, Shandong 265400, China.
  • Peifang Xu
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, People's Republic of China.
  • Yiming Sun
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, People's Republic of China.
  • Ji Shao
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Yifan Zhou
    Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Huimin Li
    a Department of Pharmacy , Special Drugs R&D Center of People's Armed Police Forces , Logistics University of Chinese People's Armed Police Forces , Tianjin , China.
  • Lixia Lou
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Qi Miao
    Chief of Cardiac Surgery, Peking Union Medical College Hospital, Beijing, China.
  • Juan Ye
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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