Efficacy of preoperative prophylactic application of betamethasone on postoperative nausea and vomiting in patients undergoing total knee arthroplasty: a prospective randomized controlled trial.

Journal: Frontiers in medicine
Published Date: Dec 17, 2024

Abstract

BACKGROUND: The demand for total knee arthroplasty (TKA) is increasing, yet postoperative nausea and vomiting (PONV) significantly hinder patient recovery. Preoperative prophylactic administration of glucocorticoids can alleviate PONV, with betamethasone showing promising results in breast and cardiac surgeries. However, its efficacy in TKA patients remains unclear. This study evaluates the efficacy and safety of preoperative betamethasone for PONV in TKA patients through a prospective randomized controlled trial (RCT).

Authors

  • Xiaobo Sun
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Qunli Dou
    The First Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, China.
  • Bowei Li
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Guoyang Bai
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Kai Qin
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Jianbing Ma
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Fudong Yao
    Department of Orthopedics, Baoji Central Hospital, Baoji, Shaanxi, China.
  • Yuanchi Huang
    Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Keywords

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