Detection and prevalence of avian influenza epidemic in the southwest of Poyang Lake and analysis of the influence of meteorological factors.

Journal: One health (Amsterdam, Netherlands)
Published Date: Apr 21, 2025

Abstract

Recently, the epidemiological profile of avian influenza has changed dramatically worldwide. Avian influenza sampling and surveillance of wholesale and retail markets in Nanchang, the largest city in the southwestern region of Poyang Lake, have been conducted since 2017. The transmission pattern of avian influenza in this region was comprehensively evaluated in multiple dimensions including time, subtype changes, seasonality and meteorological factors. Samples were tested for avian influenza A virus nucleic acids using real-time reverse transcription polymerase chain reaction, and positive results were typed. Wavelet coherence analysis was used to reveal the time-frequency variation in meteorological factors associated with avian influenza. The random forest algorithm was used to perform a multifactorial analysis of meteorological factors. Results revealed that the highest avian influenza positivity rate of 42.29 % (95 % CI: 41.18-43.41) occurred in summer. Meteorological factors were found to be significantly associated with the avian influenza positivity rate on a periodic basis. Random forest analysis revealed significant heterogeneity between meteorological factors and changes in the positivity rates of different avian influenza subtypes. Pollution concentration significantly affected the positivity rate of different avian influenza subtypes. The effect of temperature on the positivity rate of the H5 and H9 subtypes followed the opposite pattern to that of the non-H5/H7/H9 positivity rate. In winter, positivity rates of the H5 and H9 subtypes were lower and those of the non-H5/H7/H9 samples were higher; the opposite was true in spring. There is a correlation between pollutant concentration and avian influenza positivity rate. Authorities should consider climatic conditions and the level of contaminants in the prevention and control of avian influenza and adopt different preventive and control measures according to the characteristics of the different subtypes. We recommend continued surveillance of avian influenza in the region and the adoption of a 'one-health' approach for integrated prevention and control.

Authors

  • Kang Fang
    State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Xiansheng Ni
    Nanchang Center for Disease Control and Prevention, Nanchang City, Jiangxi Province, People's Republic of China.
  • Xi Wang
    School of Information, Central University of Finance and Economics, Beijing, China.
  • Wentao Song
    Department of Colorectal Cancer Surgery, Shandong Cancer Hospital and Institute, 440 Jiyan Road, Jinan, 250117, China. songwentao676@126.com.
  • Zhiqiang Deng
    Department of Civil and Environmental Engineering, Louisiana State University, Baton Rouge, LA 70803, United States. Electronic address: zdeng@lsu.edu.
  • Zeyu Zhao
    Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Tsinghua University, Beijing 100084, China. Electronic address: zzy17@mails.tsinghua.edu.cn.
  • Wei Hua
    Food and Drug Administration, Silver Spring, Maryland, USA.
  • Zhizhong Zeng
    Jiangxi Province Hospital of Integrated Chinese and Western Medicine, People's Republic of China.
  • Wei Wang
    State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.
  • Qianqian Si
    Nanchang Center for Disease Control and Prevention, Nanchang City, Jiangxi Province, People's Republic of China.
  • Jiang Wu
    College of Energy and Mechanical Engineering, Shanghai University of Electric Power, Shanghai 200090, China. Electronic address: wjcfd2002@163.com.
  • Bo Zhang
    Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, PR China.
  • Ping Zhang
    Department of Computer Science and Engineering, The Ohio State University, USA.
  • Hui Li
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Tianmu Chen
    State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen 361102, China.

Keywords

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