Molecular Subtypes and Immune Microenvironment Characterization of the Annulus Fibrosus in Intervertebral Disc Degeneration: Insights From Translation Factor-Related Gene Analysis.

Journal: JOR spine
Published Date: Apr 7, 2025

Abstract

OBJECTIVE: This study aims to examine the role of translation factors (TF) in intervertebral disc degeneration (IVDD) and to evaluate their clinical relevance through unsupervised clustering methods.

Authors

  • Sikuan Zheng
    Department of Orthopedics The Second Affiliated Hospital of Nanchang University Nanchang Jiangxi Province China.
  • Xiaokun Zhao
    Department of Orthopedics The Second Affiliated Hospital of Nanchang University Nanchang Jiangxi Province China.
  • Hui Wu
    China Medical University College of Health Management, Shenyang 110122, Liaoning Province, China.
  • Xuhui Cuan
    Department of Orthopedics The Second Affiliated Hospital of Nanchang University Nanchang Jiangxi Province China.
  • Xigao Cheng
    Department of Orthopaedics, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China. Ndefy12160@ncu.edu.cn.
  • Dingwen He
    Department of Orthopaedics, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

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