Unraveling the interrelationship between breast cancer and endometriosis based on multi-omics analysis.

Journal: Discover oncology
Published Date: Jun 13, 2025

Abstract

BACKGROUND: Endometriosis and breast cancer are significant global health burdens affecting women worldwide. Both conditions share notable characteristics including estrogen dependence, progressive growth patterns, recurrence tendencies, and metastatic potential. Despite these biological parallels, the molecular mechanisms connecting these conditions remain incompletely characterized. This study aimed to identify shared gene signatures and underlying molecular processes in breast cancer and endometriosis.

Authors

  • Jie Yang
    Key Laboratory of Development and Maternal and Child Diseases of Sichuan Province, Department of Pediatrics, Sichuan University, Chengdu, China.
  • Ping-Ting Li
    Department of Pharmacy, Shanghai Geriatric Medical Center, Shanghai, 201104, China.
  • Sheng-Ying Xi
    Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

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