Assessment of outcomes and machine Learning-based models to predict local failure risk following stereotactic radiosurgery for small brain metastases.

Journal: Journal of neuro-oncology
Published Date: Jun 13, 2025

Abstract

INTRODUCTION: We assessed the outcomes of stereotactic radiosurgery (SRS) for small intact brain metastases (SBM) (≤ 2 cm) and developed machine learning (ML) algorithms to predict the probability of local failure (LF).

Authors

  • Sreenija Yarlagadda
    Miami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
  • Yanjia Zhang
    TD - Artificial Intelligence and Machine Learning, Baptist Health South Florida, Miami, FL, 33176, USA.
  • Anshul Saxena
    TD - Artificial Intelligence and Machine Learning, Baptist Health South Florida, Miami, FL, 33176, USA.
  • Tugce Kutuk
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL.
  • Ranjini Tolakanahalli
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Haley Appel
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Robert Herrera
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Matthew D Hall
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Robert H Press
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • D Jay J Wieczorek
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Yongsook C Lee
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Tatiana Bejarano
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Michael W McDermott
    Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
  • Alonso N Gutierrez
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
  • Minesh P Mehta
    Miami Cancer Institute, Miami, Florida.
  • Rupesh Kotecha
    Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL.

Keywords

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