Incorporating automation in a cytogenetics laboratory: three practitioners' perspectives on benefits and limitations.

Journal: Molecular cytogenetics
Published Date: Jun 12, 2025

Abstract

Automation has been developed and continues to be refined for cytogenetics, including advances in the processing of samples, in analysis of conventional chromosome and fluorescence in situ hybridization (FISH) testing, and with artificial intelligence. Here we provide an overview of the various types of automation available to the cytogenetics laboratory and discuss possible benefits and limitations you may encounter based upon our collective experiences.

Authors

  • Cecelia Miller
    Department of Pathology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Jennie Thurston
    Cytogenetics and Molecular Pathology, Atrium Health and CPG Pathology, Charlotte, NC, USA.
  • Ninette Cohen
    Department of Pathology and Laboratory Medicine, Division of Cytogenetics and Molecular Pathology, North Shore University Hospital and Long Island Jewish Medical Center, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Hempstead, NY, USA. ncohen6@northwell.edu.

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