High-Output Droplet Electricity Generator for Intelligent Self-Powered Biochemical Analysis.
Journal:
Analytical chemistry
Published Date:
Jun 10, 2025
Abstract
The detection and analysis of chemical and biological substances are crucial in fields such as pharmaceuticals, disease diagnosis food safety and environmental monitoring. However, traditional analytical methods often involve complex procedures, expensive equipment, and time-consuming processes, making it challenging to achieve high sensitivity, reliability, portability, and real-time detection. To overcome these challenges, we propose a miniaturized intelligent self-powered e-tongue (MISET) that introduces key innovations in liquid sensing technology. MISET features a confined liquid sensing environment, which significantly enhances signal stability by minimizing external interference and eliminating issues related to uncontrolled liquid-solid contact angles. Furthermore, it integrates a droplet energy generation (DEG) mechanism, transforming conventional interface-limited charge transfer into a bulk effect, thereby greatly improving charge transfer efficiency and boosting output signal intensity. This advancement not only enhances detection sensitivity but also substantially lowers the detection limit. Additionally, MISET leverages deep learning-assisted analysis to optimize signal processing and pattern recognition, further improving its accuracy and reliability. By addressing the limitations of existing electronic tongue systems, MISET represents a breakthrough in self-powered liquid sensing, offering a more stable, sensitive, and efficient approach for chemical and biological analysis.