Comparison of a novel gamified binocular therapy and standard monocular patching therapy in treating unilateral amblyopia in young children: a prospective, multicenter, randomized controlled trial.

Journal: Trials
Published Date: Jun 20, 2025

Abstract

BACKGROUND: Amblyopia is a leading cause of visual impairment in children, and conventional treatments often encounter challenges related to poor compliance and adverse psychosocial effects. Recent advancements in treatment approaches have evolved beyond merely suppressing the dominant eye, now focusing on improving binocular visual function. Binocular therapy has emerged as a promising and innovative approach. The study evaluates the efficacy of a novel gamified binocular therapy for treating unilateral amblyopia on comprehensive visual functions.

Authors

  • Wenqing Zhu
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
  • Jiawei Zhang
    a Department of Pharmacy , Special Drugs R&D Center of People's Armed Police Forces , Logistics University of Chinese People's Armed Police Forces , Tianjin , China.
  • Heying Zhang
    BOKE Digital Health Research Institute, BOKE Medical Technology (Shanghai) Co., Ltd., Shanghai, China.
  • Jianjuan Zhao
    BOKE Digital Health Research Institute, BOKE Medical Technology (Shanghai) Co., Ltd., Shanghai, China.
  • Jin Lin
    Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Chanling Hu
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
  • Rui Liu
    School of Education, China West Normal University, Nanchong, Sichuan, China.

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