Generalizable model to predict new or progressing compression fractures in tumor-infiltrated thoracolumbar vertebrae in an all-comer population.
Journal:
Journal of neurosurgery. Spine
Published Date:
Jun 20, 2025
Abstract
OBJECTIVE: Neurosurgical evaluation is required in the setting of spinal metastases at high risk for leading to a vertebral body fracture. Both irradiated and nonirradiated vertebrae are affected. Understanding fracture risk is critical in determining management, including follow-up timing and prophylactic interventions. Herein, the authors report the results of a machine learning model that predicts the development or progression of a pathological vertebral compression fracture (VCF) in metastatic tumor-infiltrated thoracolumbar vertebrae in an all-comer population.
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